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New research led by Alyssa Hasty shows that diet-induced weight loss in obese individuals increases levels of a white blood cell that promotes metabolic health in fatty tissues, but not in the liver.

Mukhtar Ahmed and colleagues say the methods they employed to understand the mechanisms by which exocysts--protein complexes essential to life--function have the potential to revolutionize our understanding of cell dynamics.

The report authored by Margaret Adgent adds to the increasing evidence supporting the reproductive health consequences of early-life exposure to soy formula.

The grant will support Mary Philip's research to develop an organoid model — a miniature cell model of a functioning organ — of the liver to enable three-dimensional observation of immune-cancer interactions at the single-cell level at the earliest stages of cancer development.

Filling opioid prescriptions after giving birth raises the risk of prolonged use of the drugs in the following year.

New research by John Karijolich and colleagues have found that RNA, not viruses, activate the sentry enzymes that serve as the first line of defense against viruses.

The findings reinforce guidelines for cautious use of antipsychotics in younger populations, according to senior author Wayne Ray.

Research led by James Crowe, Jr., could lead to the first effective treatment for this dangerous mosquito-transmitted infection.

The study will test the safety of a new cervical cancer vaccine for women who already have a significant presence of precancerous cells.

A complete map of gene expression for the worm may help address broad questions in neuroscience about how gene expression programs establish diverse sets of neurons and how genetic differences contribute to neuronal function in healthy and disease conditions.

Research led by Billy Hudson has identified an antibody associated with pulmonary-renal syndrome, a rare autoimmune condition.

Changing the gut microbiome to beat illness really does hold great potential, but first scientists must answer what constitutes a healthy gut microbiome and in whom. Read More

Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding could lead to improved ways to study and treat diabetes.

New research by Jonathan Lehman and Pierre Massion have identfied a bioimarker that suggests poor prognosis for small-cell lung cancer, as well as potential target for new therapies.

Results of the study suggest the prospect of an array of individual and societal benefits to personalized medicine, as well as risks for physical, dignitary, group, economic, psychological and legal harms, many of which may have been over-emphasized or overlooked in the literature.

Tonia Rex and David Calkins were recently awarded National Eye Institute grants totaling $6.8 million over five years to develop new treatments for optic neuropathies and glaucoma, the leading cause of irreversible blindness.

A recent study led by Xiao-Ou Shu and colleagues found that green tea drinking was associated with increased risk of type 2 diabetes in Chinese adults, possibly due to the use of pesticides on tea plants--though the researchers call for further study of the exact mechanism.

Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies.

People with diabetes may be prone to more skin infections due to an overabundance of a compound that controls inflammation in the body.

In the first large-scale analysis of cardiovascular complications linked to immune checkpoint inhibitors, Vanderbilt researchers have identified several of the conditions that arise and have determined that they usually appear early in treatment.