ÌÇÐÄ´«Ã½

Older patients with a diagnosis of chronic sinusitis have a unique inflammatory signature that may render them less responsive to steroid treatment, according to new research led by Justin Turner.

Walter Chazin and colleagues have identified how a chemical "switch" in DNA primase, an enzyme essential to the replication of our genomes, works in order to hand off genetic information to the next enzyme.

Carlos Lopez, Tina Iverson and Vsevolod Gurevich propose that a conveyer belt best describes the mechanism by which cellular signals are handed off from enzyme to enzyme in the brain.

Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop. Read More

An unexpected finding by Rachana Haliyur during the cellular analysis of human pancreatic tissue has revealed new information about a rare type of diabetes and underscores the importance of genetic testing for some individuals diagnosed with type 1 diabetes.

Brian Engelhardt is studying why as many as 50 percent of stem cell transplant recipients develop diabetes.

David Aronoff and colleagues report an increased risk of the serious gastrointestinal infection C. diff following the use of NSAID pain relievers.

Knowing which neurons are involved in the eye signal blending process also opens the door to targeted brain therapies that reach well beyond eye patches. Read More

Psychiatrists diagnose people with schizophrenia, ADHD, bipolar disorder and other mental illnesses by spending time with them, looking for the particular behavior symptoms of each. What follows can be a hit-or-miss series of medications and dosages until disruptive behaviors go away. By deciphering the circuitry of the medial frontal cortex… Read More

A large-scale study conducted among East Asians and led by Vanderbilt researchers has identified multiple, previously unknown genetic risk factors for colorectal cancer.

A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery.

Craig Lindsley, co-director of the Vanderbilt Center for Neuroscience Drug Discovery, has been named a fellow of the National Academy of Inventors.

In one of the largest studies of its kind, an international research team led by 20 Vanderbilt University scientists has discovered more than 200 new genetic variations associated with high blood pressure.

A research team led by Russell Rothman has been approved for a $7 million research funding award from the Patient-Centered Outcomes Research Institute to conduct a trial comparing clinic and consumer information technology approaches to promote healthy behaviors and prevent early childhood obesity.

Boehringer Ingelheim and Vanderbilt Center for Neuroscience Drug Discovery today announced two new global agreements to investigate, develop and commercialize novel small molecules targeting two distinct G-protein coupled receptors known to engage in the modulation of certain brain circuitries, which are altered in neuropsychiatric conditions such as schizophrenia. Read More

Vanderbilt University researchers are working to understand how people with schizophrenia experience emotion through their bodies. Read More

New research led by Rebecca Cook demonstrates that an antiviral receptor called RIG-I has potent immunogenic and therapeutic effects in breast cancer.

A neural mapping approach that pegs results from more than two dozen previous Alzheimer’s studies found that reproducibility improves when trying to isolate symptoms to a brain network rather than a single area of the brain.

A randomized trial by Vanderbilt-Ingram Cancer Center researchers indicates that magnesium optimizes vitamin D status, raising it in people with deficient levels and lowering it in people with high levels.

Vanderbilt School of Medicine and Peabody College have established a transinstitutional Policies for Action Research Hub to better understand and develop recommendations to address the needs of some of Tennessee’s most vulnerable children, including those in immigrant families and with prenatal exposure to opioids.