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New faculty: Ren茫 A. S. Robinson, associate professor of chemistry

Ren茫 Robinson, associate professor of chemistry (Daniel Dubois/Vanderbilt)

interest in aging dates back to her childhood. Her mother spent her spare time as a caregiver attending to elderly people with dementia. 鈥淭he physical and mental changes I saw in these individuals touched my heart,鈥 Robinson recalled.

Now an analytic chemist, Robinson is investigating the science behind this very human condition. She is employing the emerging field of proteomics to study the process of aging as well as neurodegenerative diseases like Alzheimer鈥檚.

A beloved teacher at her Louisville, Kentucky, high school inspired Robinson鈥檚 interest in chemistry, spurring her to earn a bachelor鈥檚 in chemistry at the University of Louisville before pursuing a doctorate in chemistry at Indiana University. At the time, her laboratory at IU was doing pioneering research studying proteins in simple ways using an instrument called an ion-mobility mass spectrometer, which can simultaneously measure the size and mass of big biomolecules like proteins. This put her at the forefront of the emerging field of proteomics鈥攖he study of proteins that come in myriad sizes, shapes and configurations and are the basic components of living cells.

After two years as a postdoctoral fellow at the University of Kentucky, Robinson joined the chemistry department at the University of Pittsburgh. There she established a research program using proteomics to study aging, Alzheimer鈥檚 and other applications relevant to human health. Her efforts prompted Chemical and Engineering 糖心传媒 to give her its Talented Twelve Award in 2016, identifying her as one of the world鈥檚 brightest young minds in the field of chemistry.

When her Vanderbilt lab is set up, Robinson plans to explore the role that peripheral organs鈥攕uch as the heart, liver and kidneys鈥攑lay in Alzheimer鈥檚. Specifically, she will be looking for changes in the proteins that these organs produce that are carried to the brain and might trigger the disease, demonstrating its systemwide complexity. She also will be studying the role of lipid-related proteins in Alzheimer鈥檚 and their contribution to health disparities in the disease.

I don鈥檛 have any problem with taking apart a mass-spec instrument to see how it works or troubleshooting to bring it back online.

Robinson said she enjoys figuring out ways to improve the complex scientific instruments involved in her research. 鈥淢y dad was a mechanic, so I am comfortable fixing things. [rquote]I don鈥檛 have any problem with taking apart a mass-spec instrument to see how it works or troubleshooting to bring it back online,鈥漑/rquote] she said. One of the projects she will be pursuing at Vanderbilt is the development of technology capable of fingerprinting proteins in considerably more samples at the same time than the current state-of-the-art instruments.

Robinson is an inaugural recipient of the Dorothy J. Wingfield Phillips Chancellor鈥檚 Faculty Fellowship. Named in honor of Phillips, BA鈥67, the first African American woman to receive an undergraduate degree from Vanderbilt, the fellowship supports midcareer faculty members who are leaders in diversity in STEM at the university.

One reason Robinson chose Vanderbilt is that the , campus and Medical Center have all the resources that she needs to propel her research program to another level. 鈥淭here鈥檚 something special and very exciting happening here at Vanderbilt, and I feel enthusiastic to be a part of this evolving time in the university鈥檚 history,鈥 she said.

View the聽聽of new Vanderbilt University faculty for 2017-18.